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3^rd International Conference on the Scientific and Clinical
Applications of Magnetic Carriers
May 3 � 6, 2000
Rostock, Germany

Scientific Program

Tuesday, May 2, 2000
16:00	Registration desk open
20:00	Welcome Reception Hotel Neptun
Wednesday, May 3, 2000
	Opening session
8:30	Sch�tt Wolfgang	Rostock	Germany	Welcome to the 3rd International Magnetic Carrier Meeting
8:40	Klinkmann Horst	Rostock	Germany	Opening speech by the President of the World Apheresis Organization
9:00	H�feli Urs	Cleveland	U.S.A.	Happenings of the last 2 years: A very subjective, unscientific review
9:15
	Preparation and characterization of magnetic carriers
9:15	Azevedo Ricardo	Brasilia	Brazil	Fibrosis induced by a double-coated magnetite-based magnetic fluid in mice
9:30	Carpenter Everett	Washington	U.S.A.	Iron nanoparticles as potential magnetic carriers
9:45	Darashkevitch Oleg	Minsk	Belarus	In vitro kinetic study of cortisol release from magnetically responsive particles coated with dibutyrylchitin
10:00	Coffee break / poster session / exhibitors
10:30	Kent Tom	Arvada	U.S.A.	INVITED TALK: Historical background on magnetic particle drug delivery
11:00	Duguet Etienne	Bordeaux	France	Dissymmetrisation as a first step for new difunctional particles
11:15	Koneracka Martina	Kosice	Slovakia	Direct binding procedure of proteins and enzymes to fine magnetic particles
11:30	Morais Paulo Cesar	Brasilia	Brazil	Synthesis and characterization of cobalt ferrite-based ionic ferrofluids: a nanoparticle size control approach
11:45	Lacava Leandro	Brasilia	Brazil	Nanoparticle sizing: a comparative study using atomic force microscopy, transmission electron microscopy, and ferromagnetic resonance
12:00	Margel Shlomo	Ramat-Gan	Israel	Functional magnetic & non-magnetic polymeric nanoparticles of narrow size distribution: design, synthesis, & biomedical applications
12:15	Lunch on the boat (sponsored by Merck Eurolab) / group picture
	Preparation and characterization of magnetic carriers / continued
14:30	Rao K.V.	Stockholm	Sweden	INVITED TALK: AC susceptibility techniques to investigate magnetic carriers
14:45	Rudershausen Sandra	Rostock	Germany	Improved properties of magnetic particles by combination of different polymer materials as particle matrix
15:00	Voigt Andreas	Potsdam	Germany	Novel polyelectrolyte micro- and nanocapsules as magnetic carriers
15:15	Riffle Judy	Blacksburg	U.S.A.	Magnetic silicone fluids and films
15:30	Voltairas Panagiotes	Ioannina	Greece	Elastic stability of silicone ferrofluid internal tamponade in retinal detachment surgery
15:45	Coffee break / poster session / exhibitors
16:00
16:00	Magnetic liposomes
16:15	De Cuyper Marcel	Kortrijk	Belgium	INVITED TALK: Magnetoliposomes
16:45	Babinec Peter	Bratislava	Slovakia	Efficient magnetic targeting of magnetoliposomes
17:00	Kuznetsov Anatoly	Moscow	Russia	Application of liposomes for magnetically guided transport of myorelaxants and anti-cancer photodynamic drugs
17:15	Reszka Regina	Berlin	Germany	Gene transfer using the cationic lipid-magnetosome-DNA-complexes (CLMDC)
17:15
	Hyperthermia with magnetic microspheres
17:30	Brusentsov Nikolai	Moscow	Russia	Evaluation of ferrimagnetic fluids, ferri- and ferromagnetic suspensions for site specific RF-induced hyperthermia of sarcoma cells in vitro
17:45	Hiergeist Robert	Jena	Germany	High loss ferromagnetic magnetite suspensions for application in RF-magnetic hyperthermia
18:00	Jordan Andreas	Berlin	Germany	Clinical application of magnetic fluid hyperthermia (MFH) for local tumor treatment: rationale and method to intensify local efficacy
18:15	Shinkai Masashige	Nagoya	Japan	Intracellular hyperthermia for cancer using functional magnetic particles: applications to brain tumor and tongue tumor

18:30	Explore and enjoy Warnem�nde on your own !

Thursday, May 4, 2000

	Magnetic carriers in molecular biology
8:30	Ela�ssari Abdelhamid	Lyon	France	Hydrophilic magnetic latex for nucleic acid extraction, purification and concentration
8:45	Nordhoff Eckhard	Berlin	Germany	Magnetic carriers and MALDI-MS - an analytical alliance in genomics and proteomics
9:00	Oster J�rgen	Baesweiler	Germany	Novel magnetic beads for rapid and efficient separation of specific or unspecific nucleic acid sequences
9:15	Pietil� Johanna	Turku	Finland	Automated purification of PCR products from Borrelia species with KingFisher magnetic particle processor prior to the genome sequencing
9:30	Rauth Holger	Berlin	Germany	Magnetic beads purification of DNA-new products and applications
9:45	Coffee break / poster session / exhibitors
10:15
10:15	Magnetic assays
10:15	Connolly Joan	Nedlands	Australia	Biosensors based on time-dependent properties of magnetic fluids
10:30	Da Silva Maria de Fatima	Brasilia	Brazil	Use of the ferromagnetic resonance to investigate the time decay of magnetic fluids endovenously administrated in mice
10:45	Grossman Helene	Berkeley	U.S.A.	Magneto-Immunoassay using a high-Tc SQUID microscope
11:00	Haik Yousef	Tallahassee	U.S.A.	Application of magnetic microspheres in immunoassays: design of point of care device to measure myoglobin levels in blood
11:15	K�titz Roman	Berlin	Germany	Analysis of magnetic nanoparticle relaxation signals and application for the detection of biological binding processes
11:30	Lange Julia	Berlin	Germany	Magnetic relaxation immunoassays: selected in vitro experiments
11:45	Lasson Emilie	Skoyen	Norway	Dynabeads in cancer research and treatment
60	12:00	Lunch

	Magnetic assays / continued
13:00	Miller Michael	Washington	U.S.A.	A DNA array sensor utilizing magnetic microbeads and magnetoelectronic detection
13:15	Mornet Stephane	Pessac	France	Y3Fe(5-x)AlxO12 garnet submicronic particles for biomedical applications
13:30	Safarik Ivo	Ceske Budejovice	Czech Rp.	Application of magnetic cross-linked erythrocytes for the isolation and purification of proteolytic enzymes
13:45	Studabaker William	Raleigh	U.S.A.	Magnetic particles in coagulation testing
14:00
	Therapeutic applications of magnetic carriers
14:00	Alexiou Christoph	Munich	Germany	Cancer treatment with intraarterial "Magnetic drug targeting"
14:15	Belousov Andrey	Kharkov	Ukraine	Effects of Belousov's magnet-controlled sorbent on parameters of acid-base equilibrium in blood and processes of glycolysis in erythrocytes
14:30	Flores George Anthony	Long Beach	U.S.A.	In-vitro investigation of blood embolization in cancer treatment using magnetorheological fluids
14:45	Coffee break / poster session / exhibitors
15:15	Pulfer Sharon	Philadelphia	U.S.A.	INVITED TALK: Magnetic brain tumor targeting
15:45	H�feli Urs	Cleveland	U.S.A.	Radiolabeling of magnetic microspheres with Re-188
16:00	Sieben Stefan	Halle	Germany	Comparison of different particles and methods for magnetic isolation of circulating tumor cells
16:15	Komissarova Lyubov	Moscow	Russia	Absorptive capacity of new magnetic carriers
16:30	Kuznetsov Anatoly	Moscow	Russia	Application of magnetic particles in otiatria
16:45	Moeller Winfried	Gauting	Germany	Alveolar macrophage functions measured by magnetic microparticles in vivo and in vitro
17:00	Mykhaylyk Olga	Kyiv	Ukraine	Peculiarities of signal transduction on ecdysteron and cholesterol magnetic conjugates binding with specific erythrocyte surface receptors
17:15	End of session

19:30	Banquet in the sky bar (top floor) of Hotel Neptun

Friday, May 5, 2000

	Magnetic carriers as contrast agents
8:30	Billotey Claire	Paris	France	Analysis of biological distribution of magnetic nanoparticles in mouse by MRI
8:45	Dudchenko Nataliya	Kyiv	Ukraine	Glial brain tumor targeting in rats using magnetite nanoparticles: a basis for MRI contrast enhancement and targeted drug delivery
9:00	Lacava Zulmira	Brasilia	Brazil	Distribution of a dextran-coated magnetic fluid in mice tissues investigated by ferromagnetic resonance measurements
9:15	Pardoe Heath	Nedlands	Australia	Nanoscale magnetic particles suspended in agar gels: synthesis, characterisation, and use in testing MRI based localization in biological systems
9:30	St. Pierre Tim	Nedlands	Australia	Quantitative mapping of the distribution of magnetic carriers within the liver using magnetic resonance imaging
9:45	Warzemann Lutz	Jena	Germany	Spatially resolved relaxation measurements of magnetic nanoparticles as a novel tool for in vivo imaging
10:00	Coffee break / poster session / exhibitors
10:30
	Magnetic cell separation
10:30	Friedlaender Fritz	West Lafayette	U.S.A.	INVITED TALK: Magnetic field gradients, a short history of some of their medical and general applications, and a look into the future
11:00	Chalmers Jeffrey	Columbus	U.S.A.	Evaluation of the performance of a commercial, batch immunomagnetic cell separation system separating CD34+ cord blood cells
11:15	Chatterjee Jhunu	Tallahassee	U.S.A.	Modification of polystyrene based magnetic microspheres for separation of red blood cells; comparison with albumin based microspheres
11:30	Bennett Richard	Elk Grove Village	U.S.A.	Magnetic design considerations for devices and particles used in biological high gradient magnetic separation [HGMS]
11:45	Krauth�user Susanne	Bergisch Gladbach	Germany	New innovative methods using high gradient magnetic cell sorting (MACS)
12:00	Hoyos Mauricio	Paris	France	Hydrodynamic separation of magnetic particles and magnetically-labeled blood cells a quadrupole magnetic field
12:15	Krauth�user Susanne	Bergisch Gladbach	Germany	Automated high gradient magnetic cell sorting (MACS) systems for biomedical research and clinical applications
12:30	Wilhelm Claire	Paris	France	Quantification of particle uptake in mouse macrophages. Magnetic endosomes: a non invasive intracellular tool.
90	12:45	Lunch

	14:00	Opening ceremony of the satellite meeting "Adsorption technologies and blood purification procedures"

	Magnetic cell separation / continued
14:15	Kraeft Stine-Kathrein	Boston	U.S.A.	Immunomagnetic enrichment for the detection and characterization of lung cancer cells in peripheral blood
14:30	Liberti Paul	Huntingdon Valley	U.S.A.	Optimization of ferrofluids and protocols for the enrichment of breast tumor cells in blood
14:45	Perrin-Cocon Laure	Grenoble	France	Use of magnetic nanobeads for intracellular studies of antigen processing
15:00	Sun Wenrong	Guelph	Canada	Magnetic separation of Salmonella enteritidis using a bacteriophage based biosorbent
15:15	Todd Paul	Greenville	U.S.A.	Multistage magnetic particle separator
15:30	Zborowski Maciej	Cleveland	U.S.A.	Rare cancer cell isolation by magnetic cell deposition on microscopic glass slides
15:45	Coffee break

	Magnetophoresis and image analysis
16:15	Chalmers Jeffrey	Columbus	U.S.A.	Quantification of magnetophoretic mobility with cell tracking velocimetry: current and potential applications
16:30	Kuznetsov Oleg	Lafayette	U.S.A.	Analysis of the gravisensing system and viscoelasticity of Chara rhizoids by intracellular magnetophoresis
16:45	Moore Lee	Cleveland	U.S.A.	The use of magnetite-doped polymeric microspheres in calibrating cell tracking velocimetry
17:00	Tchikov Vladimir	Kiel	Germany	Application of magnetocytometry for the characterization of immunomagnetic particles

17:30	Departure for bus tour to Teterow in front of Hotel Neptun
18:30	Visit of the Biomedical Technology Center in Teterow
19:00	"Wild Boar Grill Party" in Teterow
22:00	Return to hotels

Our Satellite Symposium, the International Conference about "Adsorption Technologies and Blood Purification Procedures" will start on Friday, May 5 at 14:00, as a parallel session.